OpCoBe
Operant Conditioning and Behavioural Test Equipment
Empower your research with world class equipment
from the world’s top manufacturers
TOW Intelligent Technology
TOW-INT Tech supplies specialist laboratory equipment for respiratory and biomedical research, with a focus on preclinical studies involving animal models, inhalation science, pulmonary function, and aerosol exposure.
Its product range supports researchers studying lung function, respiratory disease, inhaled medicines, toxicology, environmental exposure, and metabolic responses. This includes systems for whole-body and nose-only inhalation exposure, pulmonary function testing, nebulised drug delivery, aerosol and smoke generation, gas control, plethysmography, respirometry, and related physiological measurement.
The company’s equipment is aimed at universities, pharmaceutical companies, contract research organisations, and life science laboratories that need reliable tools to investigate breathing mechanics, respiratory therapies, disease progression, and the effects of airborne substances in controlled research settings.
Pulmonary Function
Whole-body Plethysmography System for Mice and Rats (WBP-4MR)
A 4-channel system designed for use with both mice and rats, making it the most flexible option of the three Plethysmography systems. It measures the same core respiratory parameters in conscious, unrestrained animals and supports respiratory pharmacology, toxicology, AHR testing, long-term follow-up and repetitive screening.
Whole-body Plethysmography System for Mice(WBP-4M)
A 4-channel system designed specifically for mice. Like the rat version, it allows non-invasive respiratory measurement without anaesthesia or surgical airway procedures. It supports multi-channel monitoring, automatic calibration, optional aerosol atomisation, food and water ports for long-term studies, and software export to Excel or TXT.
Whole-body Plethysmography System for Rats(WBP-4R)
A 4-channel whole-body plethysmography system designed specifically for rats. It measures respiratory parameters in conscious, unrestrained animals, including respiratory rate, tidal volume and airway hyperresponsiveness. It is used for respiratory disease research, safety pharmacology, toxicology, sleep apnoea studies and long-term respiratory monitoring.
Non-Invasive Airway Mechanics(NAM)
The Non-Invasive Airway Mechanics (NAM) developed by Tow-Int Tech can measure the respiratory parameters of awake and restrained animals. It can measure nasal flow and thoracic flow, specific airway resistance (sRaw), and specific airway conductance (sGaw) respectively.
Whole-body Plethysmography System for Rats(WBP-8R)
The WBP-8R is the rat version of the same 4-channel whole-body plethysmography platform. It is designed to monitor respiratory function in rats while they remain conscious and unrestrained, avoiding anaesthesia and invasive airway procedures. It measures the same core respiratory parameters, including respiratory rate, tidal volume, peak inspiratory/expiratory flow, minute ventilation and enhanced pause, and is used for respiratory pharmacology, safety pharmacology, inhalation toxicology, environmental toxicology and long-term respiratory monitoring.
Whole-body Plethysmography System for Rats(WBP-8R)
The WBP-8M is an 8-channel whole-body plethysmography system designed specifically for mice. It measures respiratory parameters in conscious, unrestrained animals, including respiratory rate, tidal volume and airway hyperresponsiveness. It is suitable for mouse respiratory disease models, drug screening, toxicology studies, sleep apnoea research and long-term follow-up experiments. The system supports multi-channel simultaneous monitoring, automatic calibration, optional aerosol atomisation, food and water ports for longer studies, and software export to Excel or TXT.
Pulmonary Function Test System
PFT System is a comprehensive evaluation system for the respiratory and lung function of animals. It can measure airway resistance, lung compliance, FEV, FVC, FEV0.1/FVC, FEV0.2/FVC, FEF, FRC, EF50, and other indicators. It can be used in mice, rats, guinea pigs, and other animals, other sizes fro larger animal can be customized according to customers’ requirements.
Head-Out Plethysmography System
The Head-Out Plethysmography System is a non-invasive respiratory measurement system for small animal research. It allows animals to remain conscious while their breathing is monitored through a chamber that separates the body from the head.
It is used to measure respiratory parameters such as breathing rate, tidal volume, airflow, minute ventilation and airway response. The system is suitable for asthma, COPD, lung fibrosis, toxicology, inhaled drug studies and long-term respiratory monitoring.
Non-invasive Respiratory Testing System for Unrestrained Animals
The Non-Invasive Respiratory Testing WBP System is designed to measure breathing function in conscious, unrestrained animals without the need for surgery, anaesthesia or restraint.
It uses whole-body plethysmography chambers to monitor respiratory changes in real time, making it suitable for repeated testing and long-term studies. The system can be used to assess respiratory rate, tidal volume, airflow, minute ventilation, airway response and other breathing parameters.
It is commonly used in respiratory disease research, drug screening, inhalation studies, toxicology, asthma and COPD models, and general lung function assessment in small animals.
Whole-body Plethysmography System for Rabbits and Dogs (WBP-T)
The Whole-body Plethysmography System for Rabbits and Dogs (WBP-T) is a non-invasive respiratory monitoring system designed for larger laboratory animals. It measures breathing parameters while animals remain conscious and unrestrained, avoiding the need for anaesthesia, surgery or tracheotomy.
The system can measure respiratory rate, tidal volume, airflow, minute ventilation and airway hyperresponsiveness. It is suitable for respiratory disease studies, drug screening, toxicology, inhalation research, sleep apnoea monitoring and long-term follow-up experiments.
It also supports optional aerosol drug delivery, automatic calibration, food and water ports for longer monitoring sessions, and data export through analysis software.
Whole-body Plethysmography System for NHP(WBP-P)
The WBP-P Whole-body Plethysmography System for NHP is a non-invasive respiratory monitoring system designed for non-human primates. It measures breathing parameters while the animal remains conscious and unrestrained, avoiding anaesthesia, surgery or tracheotomy.
It can be used to assess respiratory rate, tidal volume, airflow, minute ventilation, enhanced pause and airway hyperresponsiveness. The system is suitable for respiratory disease research, safety pharmacology, inhalation toxicology, environmental toxicology, sleep apnoea studies, high-altitude medicine and long-term respiratory monitoring.
The main difference from the WBP-T is the animal type and chamber size. WBP-P is designed for non-human primates, while WBP-T is designed for rabbits. Both systems perform similar whole-body respiratory monitoring, but the WBP-P is the larger system for primate studies.
Animal Expiratory Acquisition System
The Animal Expiratory Acquisition System is designed to collect and sample exhaled gas from animals for respiratory research. It includes an animal gas collection chamber, sampling bag, sampling chamber, gas collection pump and supporting pipeline accessories.
The transparent chamber allows the animal to be observed during collection, while the sampling system captures exhaled gas for later analysis. It can also be configured with optional respiratory lung function monitoring, allowing real-time measurement of animal breathing parameters.
The system is suitable for animal exhalation gas collection, respiratory studies, pulmonary function research and experiments requiring controlled gas sampling from small animals.
Portable Respirometer
The Portable Respirometer is a compact system for measuring animal breathing and respiration in research settings. It is designed for small animal studies where researchers need to monitor respiratory activity, oxygen consumption, carbon dioxide output or related metabolic changes.
Its portable design makes it suitable for flexible laboratory use, short-term respiratory testing and physiological monitoring. The system can support studies in metabolism, respiratory function, drug response, toxicology, exercise physiology and general animal behaviour research.
It is useful where researchers need a smaller, easy-to-move system for collecting respiratory data without using a large fixed laboratory setup.
Nebulization, Inhalation & Exposure
Nose-only Inhalation Exposure System for Small Animals (NOE)
The Nose-only Inhalation Exposure System for Small Animals (NOE) is designed for controlled inhalation exposure and nose-only drug administration studies in mice, rats, guinea pigs and other laboratory animals.
It delivers aerosols, dusts, nanoparticles, smoke or gases directly to the animal’s breathing zone, helping ensure consistent exposure doses across the test group. The system supports online aerosol concentration monitoring, real-time sampling and high-precision control to maintain stable exposure conditions.
It is suitable for respiratory disease modelling, inhaled drug testing, toxicology, PM2.5 research, environmental safety studies, chemical exposure studies and aerosol-based research. The system can be configured for liquid aerosol exposure or combined liquid and dry powder aerosol exposure.
Nose-only Inhalation Exposure System for Small Animal (Economic)
The Nose-only Inhalation Exposure System for Small Animal (Economic) is a lower-cost nose-only exposure system for mice, rats, guinea pigs and other small laboratory animals. It is designed for controlled inhalation exposure and nose-only administration studies using substances such as liquid aerosols, dust aerosols, nanoparticles, smoke, PM2.5, pollutants, drugs and gases.
It uses a double-chamber exposure tower, where the inner chamber delivers the aerosol to the animal and the outer chamber collects exhaled gas. This helps reduce re-inhalation of exhaled air and maintain more stable exposure conditions. The system is available in 12-channel and 24-channel economic configurations, with options for liquid aerosol exposure or combined liquid and dry powder aerosol exposure.
Multi-concentration Nose-only Inhalation Exposure System for Small Animals (NOE)
The Multi-concentration Nose-only Inhalation Exposure System for Small Animals (NOE) is designed for controlled nose-only inhalation exposure and drug administration studies in mice, rats, guinea pigs and other laboratory animals.
Its main advantage is that it can generate multiple exposure concentrations at the same time from a single aerosol source. The tower can be configured with 24 or 36 channels, with 12 channels per layer. Each layer can be controlled separately, allowing different animal groups to receive different dose levels during the same experiment.
The system uses a double-chamber exposure tower, with the inner chamber delivering aerosol directly to the animal and the outer chamber collecting exhaled gas. This helps prevent re-inhalation and improves exposure control.
It is suitable for inhaled drug testing, respiratory disease modelling, inhalation toxicology, PM2.5 research, pollutant exposure, chemical safety studies and environmental toxicology. Compared with the standard NOE system, this version is best for studies that need several dose groups running simultaneously rather than one exposure concentration at a time.
Static Cell Exposure System
The Static Cell Exposure System is an in vitro exposure system based on Air-Liquid Interface (ALI) technology. It is designed to expose mammalian cells or tissues directly to gases, aerosols, pollutants, drugs or airborne test substances while the cells are supported by culture medium below. This gives a more realistic model of tissues such as the respiratory tract, alveoli and skin compared with traditional submerged cell culture.
The system is suitable for inhalation toxicology, environmental health research, inhaled drug development, respiratory pathogen studies, cell pretreatment and high-throughput screening. It can be used with 24-well plates as standard, with optional 6-well or 96-well plate formats.
Compared with the animal nose-only exposure systems above, this system is for cell-based laboratory studies rather than live animal exposure. It is best used when researchers want to test aerosols, gases or inhaled formulations directly on cultured cells under controlled temperature, humidity, oxygen, CO₂ and pressure conditions.
Whole-Body Exposure System (WBE)
The Whole-Body Exposure System (WBE) is designed for controlled animal exposure studies in toxicology, pharmacology and environmental health research. It exposes animals such as mice, rats and guinea pigs to controlled concentrations of gases, vapours or aerosols through natural breathing routes.
Unlike a nose-only exposure system, the WBE exposes the animal’s whole body, including the skin and fur. This makes it useful for simulating more realistic exposure scenarios, such as air pollution, smoke, chemical vapours, dust, nanoparticles, pollen, PM2.5 and aerosolised drug delivery.
The system includes environmental monitoring and control for temperature, humidity, pressure, oxygen, carbon dioxide and drug concentration. It also includes exhaust treatment, stainless-steel chamber construction, lighting, UV sterilisation, video monitoring, alarm indicators and an internal spray-cleaning system.
Precision Dynamic Inhalation Exposure System
The Precision Dynamic Inhalation Exposure System is a small animal nose-only/oronasal exposure system for rodents such as mice, rats and guinea pigs. It is designed for inhalation drug delivery and controlled exposure studies using gases, liquid aerosols, dust aerosols, nanoparticles, smoke and other inhalable substances.
It supports automated operation, real-time environmental monitoring, online aerosol concentration monitoring, feedback control and real-time sample collection. The system uses high-precision flow control and a dual-chamber design, where the inner chamber delivers aerosol to the exposure ports and the outer chamber collects exhaled gases to reduce re-inhalation.
It is suitable for inhaled drug evaluation, respiratory disease modelling, PM2.5 and pollutant exposure, VOC and exhaust studies, nanomaterial safety research, pesticide and chemical inhalation testing, and smoking-related health research.
Nose-only Inhalation Exposure System for Large Animals (NOE)
The Nose-only Inhalation Exposure System for Large Animals (NOE) is designed for controlled nose-only administration and inhalation exposure studies in larger animals such as rabbits, dogs and monkeys. It is used to expose animals to inhalable substances including liquid aerosols, dust aerosols, nanoparticles, smoke, PM2.5, pollutants, drugs and gases.
The system uses a double-chamber exposure tower, where the inner chamber delivers the aerosol directly to the exposure channel and the outer chamber collects exhaled air. This helps reduce re-inhalation and improves exposure stability. It also supports online aerosol concentration detection, real-time sampling and monitoring of temperature, humidity, oxygen, carbon dioxide, pressure and drug concentration.
It differs from the small-animal NOE systems because it is configured for larger animals, with suitable immobilisers and exposure channels. The page lists a standard 10-channel configuration and is intended for respiratory disease modelling, inhalation toxicology, drug safety testing, PM2.5 research, chemical exposure and environmental safety studies.
Three Channels Nose-only Inhalation Drug Delivery System
The Three Channels Nose-only Inhalation Drug Delivery System is a simple nose-only aerosol delivery system used for animal model creation and inhaled drug research. It atomises liquid drugs into inhalable aerosols and delivers them to animals through a controlled exposure chamber for a set time and concentration.
It is designed to deliver medicine through the nose only, helping reduce drug wastage and avoid secondary dosing caused by animals licking drug residue from their fur. The system uses microporous sieve atomisation to create fine aerosol droplets, with a particle size of around 1–5 microns, suitable for deep lung deposition.
It is suitable for aerosol administration and respiratory disease modelling, including asthma, pulmonary fibrosis, chronic bronchitis and lung injury studies.
Whole-body Nebulized Drug Delivery System (AER)
The Whole-body Nebulized Drug Delivery System (AER) is used for animal model creation, sensitisation studies and inhalation exposure research. It atomises liquid medicines into inhalable aerosols and disperses them inside a whole-body exposure chamber.
Unlike the three-channel nose-only system, this system exposes the animal’s whole body inside a chamber rather than delivering the aerosol only to the nose. It is available in single and dual-channel configurations, with different chamber sizes available for small, medium or large setups.
The system uses microporous sieve atomisation to generate fine aerosol droplets of around 1–5 microns, which can reach deep into the lungs. It is suitable for aerosol administration and respiratory disease modelling, including bronchial asthma, pulmonary fibrosis, chronic bronchitis and lung injury studies.
Animal Inhalation Exposure System
The Animal Inhalation Exposure System is a configurable exposure chamber system for respiratory and inhalation research in animals such as rats, rabbits, non-human primates and other species. The chamber and monitoring module can be separated, and the chamber size can be customised for different study requirements.
The chamber uses an aluminium alloy frame with transparent PMMA panels for easy observation, with stainless steel available as an option. It includes ventilation to maintain oxygen supply and reduce CO₂ build-up, plus a built-in fan mixer to help keep aerosol concentration consistent inside the chamber.
It can be configured for different exposure types, including dry powder/PM2.5 particulate matter, liquid aerosol, cigarette smoke and diesel exhaust. Optional components include aerosol generators, temperature/humidity/O₂/CO₂ monitoring, flow regulation, exhaust treatment, aerosol concentration monitoring and particle-size detection.
Animal Smoke Exposure System
The Animal Smoke Exposure System is an automatic closed exposure system designed for COPD modelling in animals such as mice, rats and guinea pigs. It automatically generates cigarette smoke so animals can continuously inhale it under controlled conditions.
The system allows researchers to control the frequency and amount of smoke, while monitoring smoke levels and environmental conditions inside the exposure chamber in real time. It supports automated cigarette loading and lighting, smoke delivery into the fumigation chamber, environmental monitoring, exhaust adsorption and waste-gas removal.
It is mainly used for chronic obstructive pulmonary disease research, smoke-exposure modelling and respiratory toxicology studies where consistent, repeatable cigarette-smoke exposure is required.
Animal Ozone Exposure System
The Animal Ozone Exposure System is a whole-body exposure chamber designed for controlled ozone exposure studies in animals. It allows animals to be placed inside the chamber while exposed to defined ozone concentrations, making it suitable for respiratory toxicology, environmental exposure research and long-term inhalation studies.
The system can hold two medium rat cages and independently monitors and controls the chamber environment. It uses a closed micro-negative pressure design with exhaust gas treatment to help prevent leakage into the laboratory environment.
It monitors temperature, humidity, oxygen, CO₂ and ozone concentration, with ozone control listed at 0.1–8 ppm and accuracy of ±0.1 ppm. The chamber can also run automatically once parameters are set.
EcigAero Aerosol Exposure Apparatus
The EcigAero Aerosol Exposure Apparatus is designed for animal studies into the effects of repeated e-cigarette aerosol exposure. It exposes rodents to a cage-like aerosol environment to help researchers study both acute and chronic effects of e-cigarette use.
It is used for in vivo research into how e-cigarette aerosols may affect the respiratory, cardiovascular and neurological systems, as well as metabolism, addiction and carcinogenesis. The system allows researchers to control exposure dose, cigarette type, quantity, timing, interval and frequency.
The system can simulate realistic smoking behaviours, including aerosol exposure with fresh air flow between exposures. It can support longer experiments, including programmed exposure over up to 72 hours, and can be used with physiological monitoring systems such as telemetry for ECG and blood pressure. It can support 5 mice or 1 rat at one time.
Cigarette Smoke Generator
The Cigarette Smoke Generator is a multifunctional system for producing controlled cigarette smoke for inhalation and exposure research. It can automatically load and light cigarettes, generate smoke and dispose of cigarette butts, helping reduce manual handling during experiments.
The system is controlled by a touchscreen and can operate in both manual and automatic lighting modes. It includes a gas flow meter to adjust smoke output, with optional additions such as real-time smoke monitoring, an air compressor and exhaust gas adsorption.
It is used for cigarette toxicity testing, inhalation drug evaluation, respiratory disease modelling and environmental exposure studies, including COPD, asthma, lung injury, pulmonary fibrosis, pneumoconiosis and lung cancer research.
Liquid Aerosol Generator (NSF)
The Liquid Aerosol Generator (NSF) is a liquid aerosol generator designed to continuously and stably produce aerosol from liquid solutions. The output concentration can be adjusted, making it suitable for controlled aerosol generation in inhalation, exposure and environmental testing studies.
It uses a high-borosilicate glass sample bottle with a specially designed nozzle and built-in micro air compressor. High-speed airflow passes through the nozzle to shear the liquid and generate aerosol mist. Larger particles are returned to the container, while smaller aerosols are output for testing.
It is suitable for generating tracer particles, salt aerosols, PSL spheres, PAO, saline solution and drug aerosols. It can also be used for HEPA/ULPA filter efficiency testing, clean-room inspection, drug atomisation, and atomisation of bacteria or virus solutions for contamination experiments.
Inhaled Drug Testing Equipment
The Inhaled Drug Testing Equipment is designed to test inhalation products such as aerosols, powders, sprays and liquid formulations. It is used to assess delivered dose uniformity and the aerodynamic characteristics of fine particles in inhaled preparations.
The system is suitable for pharmaceutical inhalation testing and supports work with inhaled drug aerosols, powders and formulations. The page states that the equipment is designed to meet requirements from the US Pharmacopoeia, European Pharmacopoeia and Chinese Pharmacopoeia, and includes NGI impactor functionality for fine-particle analysis.
It includes features such as a variable-frequency vacuum pump, high-precision electronic flowmeter, differential pressure sensor, stainless-steel artificial throat, multi-mode testing and intelligent control functions.
Neuroscience
Smart Home Cage System for Rodents
The TOW-INT Smart Home Cage System is an automated behavioural monitoring platform for laboratory mice. It combines high-resolution infrared imaging, computer vision and AI-based analysis to track individual animals continuously in the home cage, without implants, markers or human handling.
The system can monitor 1 to 5 mice per cage and measure behaviours including locomotion, feeding, drinking, sleep and social interaction. It supports 24/7 recording, including dark-cycle monitoring, making it suitable for neuroscience, pharmacology, metabolism, sleep, ageing and behavioural research. Data can be visualised in real time and exported in CSV, Excel or video formats for further analysis.
Animal Heat Stroke Modeling Chamber HA-100
The TOW-INT HA-100 Animal Heat Stroke Modeling Chamber provides a controlled environment for preclinical heat stroke research and drug development. The chamber offers precise temperature and humidity control, with automated operation to support repeatable batch modelling studies.
Designed for laboratory convenience, the HA-100 can accommodate up to 2 large rat cages or 4 mouse cages and can be used alongside equipment such as treadmills, running wheels and fatigue meters. Key features include one-click or manual operation, controllable ventilation, CO₂ monitoring, alarm functions, gas filtration, UV sterilisation, data export and a transparent observation window for monitoring animals during experiments.
Animal Neural Research Workstation
The Animal Neural Research Workstation is an integrated system for neuroscience and behavioural studies in mice and rats. It combines neural signal recording, video tracking, metabolic monitoring, sleep analysis and optogenetic stimulation, allowing researchers to collect synchronised data from conscious, freely moving animals. Its modular design makes it suitable for studies in sleep, metabolism, behaviour and brain activity.
Small Animal Metabolism Treadmill
The Small Animal Metabolism Treadmill is designed for controlled exercise training and metabolic research in mice, rats and other small animals. It supports precise speed, incline and exhaustion monitoring, making it suitable for studies in endurance, sports injury, exercise physiology, pathology and nutritional drug research. The system includes touchscreen control, adjustable stimulation, data export and customisable channel options.
Surgery
Vaporized Hydrogen Peroxide Sterilizer
The Vaporized Hydrogen Peroxide Sterilizer provides dry, low-temperature sterilisation for enclosed spaces, air and surfaces. Using vaporised hydrogen peroxide, it helps eliminate bacteria, fungi, viruses and spores at room temperature, making it suitable for laboratories, medical facilities, cleanrooms, pharmaceutical areas and other controlled environments.
Small Animal Metabolism Treadmill
The Small Animal Metabolism Treadmill is designed for controlled exercise training and metabolic research in mice, rats and other small animals. It supports precise speed, incline and exhaustion monitoring, making it suitable for studies in endurance, sports injury, exercise physiology, pathology and nutritional drug research. The system includes touchscreen control, adjustable stimulation, data export and customisable channel options.
Small Animal Anesthesia Machine
The Small Animal Anesthesia Machine – Sevoflurane is designed for controlled inhalation anaesthesia during laboratory animal surgery and experiments. It offers fast induction and recovery, adjustable anaesthetic concentration, multiple channels for induction and maintenance, and active waste gas adsorption to support a safer working environment. It is compact, mobile and suitable for use across different experimental areas.
Animal Euthanasia System
The Animal Euthanasia System is an automated CO₂-based system for humane laboratory animal euthanasia and anaesthesia. It monitors chamber temperature, humidity, oxygen and carbon dioxide levels in real time, with adjustable flow, ventilation and maintenance settings. Suitable for mice, rats, guinea pigs and rabbits, it includes alarm functions, exhaust gas treatment and UV sterilisation for safer, controlled operation.
Surgical Operating Microscope
The Surgical Operating Microscope is designed for animal surgical anatomy, teaching and laboratory procedures requiring clear, high-resolution observation. It provides strong stereo imaging, continuous magnification, wide-angle eyepieces and adjustable LED illumination for comfortable, accurate use. With HDMI and USB output for photo and video capture, plus a flexible rotating bracket, it supports detailed observation from multiple angles.
Small Animal Ventilator
The Small Animal Ventilator supports controlled respiratory assistance for mice, rats, guinea pigs and other small animals during surgery and experimental research. It offers IPPV ventilation with volume and pressure control modes, adjustable respiratory rate, tidal volume and PEEP settings, plus real-time monitoring and safety alarms. Its compact design makes it suitable for small animal surgery, respiratory studies and related laboratory applications.
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